Dr. Juan Buades Reines

 Professional experience

• More than 40 years of experience
• internist and Coordinator of the Working Group of amyloid polyneuropathy Llatzer Son Family Hospital (2011)
• Chief of Internal Medicine and head of the medical area are Llatzer Hospital, by national competition (2001 - 2010)
• Head of the Internal Medicine Hospital of Mallorca, on merit (1996 - 2001)
• Chief of Internal Medicine Hospital Joan March, by open competition (1991 - 1996)
• Deputy Internal Medicine at Hospital Son Dureta for Competition National Opposition (1978 - 1990)
• Deputy Internal Medicine at the Hospital de Cruces, Competitive National Opposition (1977)
• MIR specializing in Internal Medicine at the Hospital de Cruces (Bilbao) (1973-1977)

...

 Education

• Bachelor of Medicine and Surgery at the Faculty of Granada (1972)
• Specialist in Internal Medicine by MIR training in the Hospital de Cruces (1973 - 1977)
• Excellent Cum Laudem PhD from the University of Barcelona (1988)
• Principal investigator of "Multicenter Study of Familial Mediterranean Fever" (1988 -1990)
• Participating in the study of Leishmania + HIV with treatment with interferon (1992)
• Prospective participant in the sensitivity of Mycobacterium tuberculosis in HIV (+) and HIV (1993)
• Participating in the study of the genetic makeup of the population "xueta" (Jews of Mallorca) and carrier detection of some diseases (1993)
• Participating in the Study of the Jewish population of Mallorca at the level of mitochondrial DNA typing and familial Mediterranean fever in this population (1993)
• Participant in the study of DNA in patients with Familial Mediterranean Fever (1996)
• Participating in the study "Genetic characterization of patients with familial Mediterranean fever (FMF)" (1998)
• Participating in the prospective and comparative study of teicoplanin versus vancomycin in the treatment of patients with infection associated with intravascular catheters (1998)
• Participating in the study "Use of healthcare resources and costs associated with the diagnosis and treatment of polyneuropathy Amilidotica Family in Spain" (2011)
• Participating in the "global, multicenter, longitudinal, observational study of patients with documented mutations amyloidosis Transthyretin (TTR) or wild-type TTR, Thaos" (2012)
• Participant in "ALN-TTRO2-002 A Phase 2 Open-Label, multi-dose, dose escalation trial to Evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous infusions of ALN-TTR02 in Patients With TTR amyloidosis" (2013)
• Principal investigator on "Study Extension Phase 3, multicenter, open, to assess the long-term safety, clinical activity and pharmacokinetics of ALN-TTR02 in patients with familial amyloid polyneuropathy who have previously been treated with ALN-TTR02. Laboratory Alnylam Boston, USA (2013)
• principal investigator in the "non-interventionist cross-sectional study on the burden of disease (CDE) in patients with familial amyloid polyneuropathy associated with transthyretin (TTR-FAP) or cardiomyopathy associated with transthyretin (TTR-MC) and caregivers." PFIZER Laboratories (2013)
• APOLLO study principal investigator of the Phase 3, randomized, double-blind, placebo-controlled, multicenter, multinational to evaluate the efficacy and safety. ALN-TTRO2. In polyneuropathy measured by transthyretin (TTR-FAP). Alnylam laboratory Boston, USA (2014)

...

 Publications and conferences

• Medicine magazine editor Balear (present)
• Author of five book chapters, 40 publications (29 national and international 11)
• 60 communications to congresses and meetings and 38 conferences

...

 Prizes and awards

• Hadassah International Prize, awarded by Hadassah Medical Relief (Israel) (1988)
• FISS grant for "multicenter study of Familial Mediterranean Fever" (1988 - 1990)

 Professional membership

• Academician of the Royal Academy of Medicine and Surgery of the Balearic Islands (1999)