Hypopituitarism is the lack of segregation of hormones by the pituitary gland that can be total or partial, depending on the degree of damage, producing changes in some organs. Furthermore, the lack of thyroid hormones and impaired reproduction can also affect blood pressure. In women, the most common manifestations of this disease are changes in menstrual cycle, decreased libido, and infertility. And in men, hypopituitarism can cause decreased muscle strength, decreased libido and erectile dysfunction. Anyway, hypopituitarism is a progressive disease, so symptoms are not too evident and usually occur gradually. Some of the most common causes of hypopituitarism are: head injuries, tumors, brain infections or radiation, genetic diseases and other disorders caused by the immune system.