Angioedema is a disease similar to hives skin but which manifests under the skin instead of the surface. Also called angioedema, it is caused by an allergic reaction although its origin is unclear. In some cases, it seems to have some relationship to exposure to sunlight, certain foods (nuts, fish, eggs ...), insect bites, fever, or allergic to certain medications. It also tends to occur in patients who have suffered an infectious process, such as lupus or leukemia. Its main symptoms are swelling of the skin, specifically around the eyes and lips, hands, feet and throat, aside from painful, itchy welts. Sometimes also it causes shortness of breath and abdominal cramps. The diagnosis is made after medical examination of the skin and throat, laboratory tests and allergy tests. Only in case of obstruction of the throat you will need to go immediately to a hospital. Treatment depends on the severity of symptoms but the most used are antihistamines, corticosteroids, epinephrine injections (in severe cases), or inhalers to open the airways.