Written by: Dr. Gaspar Mestres Alomar
Published: | Updated: 18/11/2018
Edited by: Top Doctors®

Sclerosing treatment has proven to be the most effective treatment for eliminating venules and varicose veins of the lower extremities.

This treatment consists in the injection of a substance inside the vein that produces an inflammatory reaction with obliteration and fibrosis of the vein, producing a local reaction that makes the vein disappear, the greater the reaction that occurs at the level of the vein, the recanalization rate is lower and, therefore, the chances are lower that the vein will come out again.


Sclerosing agents are basically divided into three types:

The detergents, reduce the superficial tension at the level of the wall of the glass , producing a cellular lysis, this type of sclerosantes are those that allow to foam.

The osmotics are indicated for very small vessels , produce vasospasm at their introduction and some lesions at the sites of injection. These agents tend to be hyperosmolar solutions and present risk of post-treatment pigmentation.

Chemical agents are the most commonly used for cryosclerosis. They have a high viscosity and require prolonged contact with the vessel to be treated. Your injection may be painful.


Cryosclerosis is a variant of traditional sclerosis, in which cold is associated with this process by cooling the sclerosing substance helped by carbon dioxide .

Thus, when the sclerosing agent is introduced, a vaso-spasm (contraction of the vessel) is produced, with which the sclerosing fluid remains longer in the area to be sclerosed, thus increasing its effectiveness. At the same time regulates the amount of sclerosant that is injected.

Cryosclerosis, therefore, optimizes the sclerosing treatment of small vessels. Since on the one hand it regulates the amount of sclerosant that we use, and on the other hand it makes it more effective by staying the sclerosant more time in the area to be treated.

Technique and care

All medical treatment has its advantages and disadvantages, one of the main complications of sclerosing treatment is the skin pigmentation of the area in question.. This pigmentation is secondary to the thrombotic process inside the vessel, when blood hemoglobin is mixed with sclerosing, a localized thrombus is produced, and this is what causes pigmentation to appear. With cryosclerosis the formation of this thrombus is limited, and thus the amount of thrombus is decreased, in this way, the pigmentation is lower.

Precisely because of the pigmentation it is preferable to sclerose an area more than once instead of pigmenting this area, since the pigmentations secondary to the sclerosing treatment are difficult to eliminate.

After treatment, all you have to do is wear a Class I / II elastic compression. Thanks to this we will reduce the inflammatory reaction of the treated vein and we achieve that the sclerosant is more effective in the area.

*Translated with Google translator. We apologize for any imperfection

By Dr. Gaspar Mestres Alomar
Vascular Surgery

Dr. Mestres Alomar is a renowned vascular surgeon with over 10 years of experience. He specializes in Endovascular Surgery, access for hemodialysis and peripheral artery disease, among other treatments. Currently holds Clinic Sagrada Familia in Barcelona.

*Translated with Google translator. We apologize for any imperfection

View Profile

Overall assessment of their patients