Tissue Regeneration by Growth Factors

Written by: Dr. Miguel Ángel Hernán Prado
Edited by: Top Doctors®

¿What are Growth Factors


So-called“ Growth Factors” are Protein our own cells produced and which are responsible for stimulating cell proliferation and survival and to maintain balance in the body.

The Platelet Rich Plasma or Plasma Rich in Growth Factors ( PRGF, for its acronym in English ) is a preparation that is obtained after a the spinning process blood from the patient, through which specific growth factors are released.

The application of growth factors stimulates and accelerates the process healing and regeneration of most of the tissues that make up our body.

¿That injury can be treated with growth factors


It is a technique with potential for application in many muscle pathologies ( hamstring injury ), tendon ( tendinopathy, degenerative partial tear, epicondylitis fasciitis ), ligamentous and articular ( chondropathy, osteoarthritis initial, sprained, repair meniscus ).

¿Like PRGF infiltrations are performed


To infiltrate the PRGF the first step is to obtain patient's blood through a conventional extraction process. Later this small amount of blood is centrifuged to obtain and isolate the fraction having a higher concentration of platelets, which will contain the growth factors.

To complete the process, the compound was obtained the patient was administered through direct infiltration applied to the injured area or introduced under direct vision through a arthroscopy. Sometimes it may be necessary for the infiltration takes place in operating room and a slight sedation.

¿How many are made


Usually sufficient with a single infiltration for most cases, but in some locations and in severe cases it is advisable to apply a 2 or 3, allowing a period of about 2 weeks between each.

¿What is the recovery time


Symptoms the patient begin to ease after approximately 4 to 5 weeks from the first infiltration. From that moment the discomfort gradually yield. The patient should be aware that as this is a biological therapy and no drug is necessary to take some time for his performance and therefore the improvement is not quite immediate.

¿may be complications


Sometimes there may be occasional discomfort and self-limiting in the place where was made the puncture for the infiltration or joint. As the PRGF is made by the patient's own blood and will not add any external component, it is not possible rejection or allergy is developed to implement it. Besides being a biological therapy without drugs also no contraindications related to its administration.

*Translated with Google translator. We apologize for any imperfection

By Dr. Miguel Ángel Hernán Prado
Orthopaedic Surgery

Recognized expert in arthroscopic shoulder and knee surgery, with over 20 years experience in private and public hospitals. It has pubicado numerous articles in national and international scientific journals, in addition to attending as a speaker at multiple conferences specialty. Currently, he is head of section Orthopaedic Surgery and Traumatology at the University Hospital of Santa Cristina.

*Translated with Google translator. We apologize for any imperfection

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