Lupus erythematosus: a disease that goes beyond skin

Written by: Dr. José Manuel Mascaró Galy
Published: | Updated: 21/02/2018
Edited by: Top Doctors®

The lupus erythematosus ( LE) is a complex autoimmune disease whose manifestations are varied. One of the most frequently occurs in the skin.

When a patient presents to the dermatologist consultation with lesions of lupus erythematosus may be concerned that only a limited skin painting or a manifestation of a systemic picture with possible internal organ. This is what we call a systemic lupus erythematosus or SLE. In fact the skin is the second affected quadromas in SLE patients, and skin lesions represent 4 of the 11 diagnostic criteria for SLE.

Skin Manifestations

The cutaneous manifestations of lupus erythematosus are very variable and include among others: discoid LE, LE tumido, photosensitivity, alopecia, lupus panniculitis, lupus perniosis, cutaneous vasculitis, urticaria - vasculitis, white atrophy, Raynaud's phenomenon etc.. The clinical appearance of the lesions is very variable, and can be confused with many diseases of the skin. Therefore, to make the diagnosis will be crucial to perform biopsies of skin lesions and perform analytic studies adequate to rule out SLE.

topical and systemic therapy

Treatment of LE includes some important general measures such as avoiding the sun, using broad spectrum sunscreens and quit, since the snuff worse cutaneous LE lesions and can lead to treatments fail. If it is an exclusively cutaneous LE lesions and few can be adequately treated only with topical medications (corticosteroids and immunomodulators high power ).

Forms extensive cutaneous LE and SLE tables also specify the use of systemic drugs such as antimalarials ( chloroquine, hydroxychloroquine ), systemic corticosteroids and immunosuppressant. Among the latter highlights the newest addition to the therapeutic arsenal of mycophenolate ( a drug that comes from transplantation medicine ) that is providing very good results.

*Translated with Google translator. We apologize for any imperfection

By Dr. José Manuel Mascaró Galy
Dermatology

Dr. Mascaró is a leader in Dermatology. He has more than 30 years of experience in the profession and extensive training in different fields of the specialty. In particular, its main areas of interest are autoimmune diseases of the skin (bullous diseases and connective tissue diseases), cutaneous manifestations of transplant patients (solid organ transplantation and hematopoietic stem cells), and dermatopathology (inflammatory dermatosis and immunofluorescence). ). On the other hand, throughout his professional career he has combined his care work with teaching, being Professor of Dermatology at the University of Barcelona. He also develops an important dissemination work, being the author of more than 100 international publications, as well as a regular speaker at national and international conferences. He currently works at Barnaclínic, besides being responsible for the hospitalization unit of Dermatology, the consultation of cutaneous autoimmune diseases and the consultation of cutaneous pathology of transplant patients of the Hospital Clínic de Barcelona.

*Translated with Google translator. We apologize for any imperfection

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