Long-Term Stimulation of Collagen

Written by: Dra. Maria José Maroto
Published: | Updated: 11/11/2018
Edited by: Top Doctors®

The collagen of the body is responsible for creating and maintaining the structures of the tissues that make up the body, which includes the skin, so it is a fundamental part in properties such as firmness and flexibility. The appearance of the skin will depend, to a large extent, on the particular level of collagen.

Once the forty years have passed, the organism starts to produce half as much collagen as during adolescence. This reduction of collagen, among other things, causes loss of elasticity and flexibility of the skin.

In Aesthetic Medicine there is a filling that is placed inside the skin with practically painless infiltrations, with the aim of reducing facial wrinkles or treated areas, such as hands and folds on the face.

How are the compounds that stimulate the generation of collagen?

This dermal filler is composed of a small part of hydroxyapatite which is mixed with a very mild carboxymethylcellulose gel. In addition to helping to reduce the appearance of wrinkles, they will stimulate the production of collagen in the treated area, giving it a healthier and younger appearance. Therefore, filling treatments promote the process of neocolagenesis, which consists of helping the body to produce new collagen, without requiring so much effort on the part of the organism.

Therefore , we speak of a biocompatible substance , similar to the components that the body produces naturally, so there are no risks of rejection or allergic reactions. Thus, thanks to its effectiveness in increasing and remodeling the different facial areas, it has been approved by the Food and Drug Administration (FDA) in the United States, which allows this filling to be used to improve the appearance of facial lipoatrophy ( Loss of subcutaneous fat).

Thus, this filling technique can be used in face wrinkles, either deep or small, between the fold of the nose and lips, between the eyebrows and the forehead. It can even be used to fill scars caused by wounds or even surgeries that left a mark.


In what treatments is the application of collagen recommended to achieve satisfactory results?


  • Puppet lines : well-known for their similarity to the mouths of the puppet, and are the marks that appear at both ends of the lips and that end in the chin. 
  • Nasolabial folds : wrinkles that appear between the nose and lips. 
  • Periocular wrinkles : those traditionally known as "crow's feet". 
  • Imperfections in the nose and chin filling: small touches on the nose and chin area to improve imperfections that can improve our facial appearance. 
  • Beautification of hands : enhances and rejuvenates the appearance of hands. 

In short, you get a rejuvenation and better appearance in the treated areas, achieving a natural and healthier appearance.

*Translated with Google translator. We apologize for any imperfection

By Dra. Maria José Maroto
Aesthetic Medicine

Dr. Maroto is dedicated to medicine since 1990. It combines the aesthetic medicine with homeopathic medicine. It specializes in integrative medicine aesthetic, antiaging, facial, body and hair medicine, cosmetic dermatology treatments and pre- and menopause. In 2014 he received the Professional Excellence Award by the Institute for Professional Excellence. The doctor, who has conducted numerous training courses within their specialty, is responsible for the Department of Aesthetic Medicine Integrative Medicine (CMI) Clinic.

*Translated with Google translator. We apologize for any imperfection

View Profile

Overall assessment of their patients