Parkinson's disease is caused by a degenerative brain neurological impairment. The area of the brain affected is the midbrain and substantia nigra. The most common symptoms are mild resting tremor, slowness of movement or instability and difficulty in turns on the march.
Parkinson: what it is
Parkinson's disease is a brain degenerative neurological impairment and progressive, whose ultimate cause is unknown. Cerebral involvement is mainly focused on an area of the brainstem called the midbrain, specifically the substantia nigra. The neurons of this brain part produce dopamine, which is a fundamental movements of the whole body neurotransmitter, especially automatic movements. The involvement of the substantia nigra involvement called basal ganglia is added, and then other brain areas.
Parkinson 's symptoms
The symptoms of this disease begins in several ways:- Slight tremor of rest in any Member- Slowness of movement- Gait instability- Difficulty in walking turns- Olfactory problems and constipation- depression
Causes of Parkinson
Despite the many scientific studies on the disease, we do not know the exact cause. They have been considered toxic genetic or environmental causes, which occur in some cases of Parkinson family, cause chemical. It has been shown in recent years that the disease is much broader than previously thought and the involvement of the nervous system much broader.
Diagnosis of Parkinson
The diagnosis of the disease has to become an expert in Neurology. First it will be done by neurological clinical examination, since the symptoms of tremor and slowness of movement or stiffness of limbs, may correspond to other non parquinsonianas pathologies. Also, tests should be performed as Magnetic Resonance Cerebral Neurophysiology tremor or Dat-Scan to assess brain dopaminergic system and blood tests.
Treatment for Parkinson 's
Currently there are very effective medical treatments to improve symptoms. The crown jewel in terms of medical treatment is Levo-Dopa, which is converted into dopamine to reach the patient's brain and reverses symptoms. Also, dopaminergic drugs and MAO inhibitors. Also recommended are drugs that can be prescribed in poly therapy modality to more effectively retard or transdermal patches, in some cases. treatments intragastric infusion pumps and treatments are also prescribed.Patients who do not respond to medication or who have disabling side effects can be treated by neurosurgical stimulation techniques or selective neuronal injury centers called cerebral striatum system. Neural transplants that began more than 30 years have not yielded the results, in addition to the important side effects involving expected, which has led to not continue in that line therapy. New research drugs are in line neuroprotection to slow the progression of the disease.