regenerative medicine, medicine of the XXI century. Regenerate instead of repairing

In INcTERAL, the Catalan Institute for Regenerative Teràpia de l'Aparell Locomotor, a team of orthopedic surgeons, sports doctors, physiotherapists, osteopaths, nutritionists and podiatrists join the most advanced of each of their fields knowledge and techniques to provide an overview the patient's problem and possible solutions. As a result, this multidisciplinary team, an expert in biomechanics, has incorporadoentre procedures obtaining cell groups from fatty tissue where they coexist, among other cell lines, adult mesenchymal stem cells for implantation in the patient and in the same act doctor. Dr. Andreu Arquer that, with Dr. And Dr Joaquim Punsoda. Ruben Ledesma, is one of the three founding members of the center, explains what this treatment and its applications.

Why this treatment?

Esmuyemocionante vercomolo we had always believed would be the future of medicine has come, crecedíaadía, andis already bearing results in daily practice. So far eramuyfrustrante unable to ofreceralternativasaprocesos Degenerative where for example, there was not much else to do rest or wait until the joint was completely destroyed to put a prosthesis.

What are adult stem cells?

Our whole body is originated from the union of two cells (sperm and egg) and their proliferation and subsequent differentiation in different tissues corporales.Múltiples influences (diseases, injuries, etc.) I ocasionanamenudo the loss of his integrity, but fortunately in all our body tissues are "niche" adult stem cell reserves that are still immature and can differentiate (become) in specific cell lines (muscle cells, fat, cartilage, bone, tendon, etc.). These are called "adult mesenchymal stem cells" with the capacity to generate almost all varieties of cells, but not an entire organism.

What body part adult stem cells are extracted and what they mean for medicine?

Adult mesenchymal stem cells are obtained from different sources, eg, bone puncture, called "BMSC" (Bone Marrow Stem Cells), or adipose tissue by lipoaspirate ADSC (adiposité Derived Stem Cells), to mention two of the sources more frequent collection. Each location has its advantages and disadvantages. In our center we perform such extraction subcutaneous tissue (commonly called "fat"), for ease, speed and efficiency, from which we get what is called "SVF" or "stromal vascular fraction of adipose tissue", and isolated groups cell that interest us. Thanks to the therapeutic advances achieved by biological medicine and tissue bioengineering has taken the step towards a more natural, efficient and effective medicine that power regeneration mechanisms at the expense of repair. New knowledge on the use of growth factors (GF), certain cytokines (CK) and especially of the SVF (Stromal Vascular Fraction) where among other adult stem cells, open the door to Translational lamedicina, which fosters use of treatment with our own tissues, and move what we have in abundance in a place reserve to another where it is needed to regenerate due to injury.

What are adult stem cells?

There are numerous studies (published more than 1,500 a year in major scientific journals) have demonstrated the ability of the implant of stem cells from adipose tissue to regenerate damaged tissues of the body, such as cartilage, tendons, ligaments, muscles , etc. All come from the same embryonic layer (mesoderm) that mesenchymal stem cells, and therefore have the ability to regenerate any of these tissues.

What kind of treatments are being carried out?

The experience and current studies recommend its use in degenerative joint diseases such as osteoarthritis of the hip, knee, shoulder or spine, and chronic pathologies of tendons such as tendonitis or chronic tendinopathy, complementing the various current treatments that affect the primary cause, usually biomechanics. This can get feedback from injuries that can only hardly be treated using traditional methods.

What are the treatments performed Incteral regenerative medicine?

The process is performed implant through a local anesthetic lipoaspirate. Thus we obtain cell group containing the fat tissue, from which we isolated without substantial manipulation adult mesenchymal stem cells, which subsequently will implement by simple infiltration into the injured point with a normal needle. The total duration is about two hours. The whole procedure is performed with a team under closed system developed by the company Lyposmol, which meets the highest standards of quality, biosafety, feasibility and legality. The implant is carried out at the Clinic of Nostra Senyora del Remei Barcelona medical team of Dr.. Andreu Arquer, Dr. And Dr Joaquim Punsoda. Ruben Ledesma. But also, our team conducts treatment prior to implant to prepare the area, and later, to maintain and enhance its activity with technology and physiotherapists Centre de l'Aparell Dr Locomotor. Andreu Arquer: Xavier G. Nadal Alvaro Tarrela, Berta Portales, Miquel Palau VélezyXavier. We also have the collaboration of Dr. Enric Munt and the peu Studies Centre Martin Rueda. Both the query Clinic Incteral as Nostra Senyora del Remei are pioneering spaces in regenerative medicine, and are specially equipped with the necessary elements to provide this type of intervention with the maximum guarantee.

This cell therapy (SVF), can be applied in any patient?

Yes, the great thing about this technique is the wide range of patients who are treated with it. Anyone, seaonodeportista, can benefit greatly from it and its broad therapeutic and regenerative possibilities. Although we also do in athletes of the CAR, the initial experience we have in people "walk" as any of us, queamenudo have never done high-level sport, some more thick and others thin, but they have some osteoarthritic process knee or hip is progressively limiting them in their daily lives. In our daily practice, we see how this therapy allows them to substantially improve pain and mobility, recuperandopoco little their previous abilities, like being able to walk out, up or down stairs, or just bending over to pick something up or get off the couch.

The technique we use is evaluated in athletes CAR de Sant Cugat, center with which we have established a collaboration agreement for the treatment of athletes with regenerative therapy using adult mesenchymal stem cells and other cell groups containing the fatty tissue ( SVF) with ADSC Lyspomol System® we use regularly.

The goal is to help athletes in the CAR of Sant Cugat with a chance of qualifying for the Olympic Games Rio 2016 and lesions difficult to conventional treatment, so they can benefit from this technique INcTERAL offers and allow them to prepare the Olympic Games in optimal conditions as well as those who may be injured during the Olympics so they can recover best.